Certified Emergency Nurse (CEN) Practice Test

What is the primary treatment for hemophilia A?

1. Factor 8 replacement

2. Low dose aspirin

3. Blood transfusion

4. Prednisone

The correct answer is: Factor 8 replacement

The primary treatment for hemophilia A is factor 8 replacement therapy. Hemophilia A is a genetic disorder characterized by a deficiency of clotting factor VIII, which is essential for normal blood coagulation. When individuals with hemophilia A experience bleeding episodes, they require immediate replacement of this specific clotting factor to promote clot formation and prevent excessive bleeding. Factor 8 replacement can be administered as a concentrate derived from human plasma or through recombinant technology, making it a targeted and effective treatment option. This therapy not only helps manage acute bleeding but also works as prophylaxis to prevent future bleeds in patients with severe forms of hemophilia A. Other treatments like low dose aspirin are contraindicated in patients with hemophilia, as aspirin can inhibit platelet function and exacerbate bleeding risk. Blood transfusions may be necessary in cases of acute massive bleeding but are not specific treatments for hemophilia itself; rather, they address overall blood volume and oxygen-carrying capacity. Prednisone may be used for certain autoimmune responses or complications but is not relevant as a primary treatment for hemophilia A.